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Browsing Theses and Dissertations by Author "Aira Yzabel P. Paringit"
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- ItemProximate composition and functional activities of Oudemansiella canarii (Jungh.) Hohn. mycelia(2019) Aira Yzabel P. ParingitOudemansiella canarii has flat, smooth and sticky (when moist) surface, grayish white brittle pileus with white spore print and ring-like hyaline basidiosportes. In order to establish their nutraceutical potentialities, the mycochemical composition, antioxidant, total phenolic content, cytotoxicity, teratogenic and antibacterial activity were assessed. the mycochemical screening revealed essential oils, tritepenes, coumarines, anthraquinones, tannins, flavonoids, phenols, alkaloids, steroids and coumarins. However, saponins, cardiac glycosides and fatty acids were not detected. O. canarii extract showed radical scavenging activity of 67.17% and contai9ned total phenolics 42.13 mg GAE/g. Antibacterial activity shows no inhibitory activity against S. aureus and E. coli. Delayed grwoth after 48-hour exposure to O. canarii and coagulation were the major teratogenic activities observed. The cytotoxicity assay related assay revealed that the ethanol extract of O. canarii is toxic with an LC50 value of 196.457 ug/mL. Thus, mycelia of Oudemansiella canarii contain bioactive compounds with functional activities such as antioxidant, cytotoxic and teratogenic activity.