Chemical components and biological activities of sea cucumber (Stichopus horrens) collected from Diguisit, baler, Aurora
Date
2019
Authors
Mary Anne R. Iniego
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Abstract
This paper highlighted the chemical components and biological activities (antioxidant, teratogenicity and anti-inflammatory) of S. horrens extracts. the compound present are phenols, steroids, essential oil, triterpenes, coumarins, anthrones, tannins, phenolics and flavonoids. The extracts contain 16.92% GAE/g sample and showed 41.41% radical scavenging activity. Further, the teratogenic activity of S. horrens was evaluated using hot water and aqueous crude extracts. S. horrens hot water extracts exhibited lethal and teratogenic activity on D. rerio embryo at concentration level of 10,000 ppm. The highest mortality rate was recorded at 12 hours of exposure. meanwhile, S. horrens aqueous crude efficacy showed no effect. On the other hand, the anti-inflammatory activity of S. horrens was determined using in-vitro CAM (chorioallantoic membrane assay. Highest percentage of inhibition was recorded at 1000 ug/ml with 79.38% and no inhibition was observed in the other treatments.