Antifungal, antioxidant and teratogenic property of Morus spp. leaves S54 variety [manuscript]
No Thumbnail Available
Views
...
Downloads
...
Date
2017
Authors
Johlia Lae D. Serrano
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
This study assessed the antifungal propety of Morus spp. leaves S54 variety against A. niger and R. oryzae and tested its antioxidant effects and teratogenic property. In assessing the antifungal property, haemocytometer was used. The diameter zone of inhibition were measured after 48, 72, 96 hours of incubation to the nearest millimeter using vernier caliper. Formation of zone of inhibition means effectivity of Morus spp. leaves S54 variety aginst the test pathogens and absence means resistance of the organisms to Morus spp. Ethanolic extract of Morus spp. leaves S54 variety had partially inhibited the growth of A. niger while there is no growth of inhibition of R. oryzae. For the determination of the radical scavenging activity of the crude extracts of M. alba L. S54 variety the DPPH radical scavenging activity assay by Kolak et al. (2006). The total phenolic content of the crude culture of M. alba L. S 54 variety the DPPH radical scavenging activity assay by Kolak et. al (2006). The total phenolic content of the crude culture extracts were determined using the Folin- Ciocalteu method as described by Hodzic et al. (2009). Morus spp. leaves S54 variety crude extract exhibited 12.93% of radical scavenging activity. In terms of total phenolic, Morus spp. leaves S54 variety extract contain 67 mgAAE/1g of sample. Therefore, Morus spp. leaves S54 variety had an antioxidant property. Evaluation of teratogenicity of hot waterextract of Morus spp. leaves S54 variety were observed on the 12, 24, 36, 48 hours of treatment exposure using zebrafish (Danio rerio) as a vertebrate model and showed different dysmorphic features namely growth retardation and malformation of tail and had caused mortality on zebrafish embryos.