Anti-proliferative and cytotoxic activity of Ilongot Engongot Ethnobotanicals against human breast cancer cell Line (MCF-7) using MTT Assay
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Date
2019
Authors
Lizette B. Tapang
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Abstract
Leaves and stem extract of five ethnobotanicals of the Ilongot-Engongot community of Aurora, Philippines were examined for their antiproliferative and cytotoxicity activity against human breast cancer cell lines (MCF-7) using MTT assay, a colorimetric assay that is use for measuring the metabolic activity of the cell. The tested ethnobotanicals includes Ceiba pentandra (local name: Betek), Hydrocotyle vulgaris (Local name: Gotukola), Urena lobata (Local name: Pukot), Phyllanthus urinaria (Local Name: Taltalikod), and Senna alata (Local name:Acapulco). The five ethnomedicinal plants that tested showed IC50 values > than 30 ug/ml and indicates absence of anti-cancer activity against human breast cancer cell line (MCF-7) using the MTT assay.