Mycochemical antioxidant and antimicrobial activity of Xylaria papulis collected from Paracelis, Mountain Province
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Date
2019
Authors
Emerson O. Diego
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Abstract
Mycochemical constituents, antioxidant and antimicrobial activity of Xylaria papulis collected from Paracelis, Mountain province were evaluated in this study. X. papulis exhibited secondary metabolites such as essential oil, triterpenes, coumarines, anthraquinones, tannins, flavonoids, anthrones, fatty acid, phenols, steroids and alkaloids. Additionally, DPPH radical scavenging activity of X. papulis showed 55.67%, however, it was lower than the positive control catechin which has 71.13%. On the contrary, X. papulis exhibited high total phenolic content of 43.17 mg GAE/g.
On the other hand, the ethanolic extract of X. papulis showed a mean zone of inhibition ranging from 16-18 mm. Statistical analusis revealed that the mean zone of inhibition of ethanolic extract has a significant difference with the negative control, positive control and ethanol. The zone of inhibition exhibited by the ethanolic extract has a significant difference with the negative control, positive control and ethanol. The zone of inhibition echibited by the ethanolic extract of X. papulis has an intermediate effect against Escherichia coli and Staphylococcus aureus. Furthermore, ethanolic extract of X. papulis showed low antifungal activity against Candida albicans.